Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Dioxane, an organic compound, also known as dioxane, 1,4-dioxane, is an organic substance, the molecular formula is C4H8O2. It is a colorless and transparent liquid, slightly fragrant, miscible with water, miscible most organic solvents. The compound is used in the manufacture of special fine chemicals such as medicine, cosmetics, and fragrance, as well as as a solvent, reaction medium, and extraction agent in scientific research.