cas 871700-28-6|| where to buy 6-Amino-3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-pyrimidine-2,4(1H,3H)-dione

Product Name:6-Amino-3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-pyrimidine-2,4(1H,3H)-dione

IUPAC Name:6-amino-3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

Packing Unit	Available Stock	Price($)	Quantity
CM165057-5g	in stock	ƈȃŮƈ

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: CAS NO:871700-28-6; Molecular Formula:C13H11FIN3O2; Melting Point:-; Smiles Code:O=C1N(C2CC2)C(C=C(N)N1C3=CC=C(I)C=C3F)=O; Density:

: Catalog Number:CM165057; Molecular Weight:387.15; Boiling Point:; MDL No:MFCD18207183; Storage:Store at 2-8°C.

: Pyrimidines; Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

: Cyclopropanes; Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

: Benzenes; Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.