Product Name:tert-Butyl (3-(4-chloro-2-(2-fluoro-6-methoxybenzoyl)-phenyl)prop-2-yn-1-yl)carbamate

IUPAC Name:tert-butyl N-{3-[4-chloro-2-(2-fluoro-6-methoxybenzoyl)phenyl]prop-2-yn-1-yl}carbamate

CAS:869366-70-1
Molecular Formula:C22H21ClFNO4
Purity:95%
Catalog Number:CM155405
Molecular Weight:417.86

Packing Unit Available Stock Price($) Quantity
CM155405-1g 3-4 Weeks ȤǺŸ

For R&D use only.

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Product Details

CAS NO:869366-70-1
Molecular Formula:C22H21ClFNO4
Melting Point:-
Smiles Code:O=C(OC(C)(C)C)NCC#CC1=CC=C(Cl)C=C1C(C2=C(OC)C=CC=C2F)=O
Density:
Catalog Number:CM155405
Molecular Weight:417.86
Boiling Point:
MDL No:MFCD13194156
Storage:Store at 2-8°C.

Column Infos

Alisertib
Puma Biotechnology announced the initiation of its ALISertib in CAncer (ALISCA-Lung1) Phase II trial of alisertib monotherapy for the treatment of patients with extensive stage small cell lung cancer. The ALISCA-Lung1 trial will enroll up to 60 patients with extensive stage small cell lung cancer who have progressed on or after first-line platinum-based chemotherapy and immunotherapy. The primary endpoint of the trial is objective response rate, with secondary endpoints of duration of response, disease control rate, progression-free survival and overall survival. Based upon the outcomes of the study, Puma anticipates meeting with the FDA to explore the potential for an accelerated approval pathway for alisertib in small cell lung cancer. Alisertib is an orally active and selective Aurora A kinase inhibitor, which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation.
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