Product Name:Fmoc-Val-Cit-PAB-PNP

IUPAC Name:{4-[(2S)-N-[(1S)-1-carbamoyl-4-(carbamoylamino)butyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]phenyl}methyl 4-nitrophenyl carbonate

CAS:863971-53-3
Molecular Formula:C40H42N6O10
Purity:97%
Catalog Number:CM255395
Molecular Weight:766.81

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CM255395-10g in stock ǙľIJǙ

For R&D use only.

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Product Details

CAS NO:863971-53-3
Molecular Formula:C40H42N6O10
Melting Point:-
Smiles Code:O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@@H](C(C)C)C(N([C@@H](CCCNC(N)=O)C(N)=O)C4=CC=C(COC(OC5=CC=C([N+]([O-])=O)C=C5)=O)C=C4)=O
Density:
Catalog Number:CM255395
Molecular Weight:766.81
Boiling Point:
MDL No:MFCD22200278
Storage:Keep in dark place, store at 2-8°C.

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Cleavable linkers
Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.
Peptide linkers
Peptide linkers belong to protease-sensitivity linkers (also called enzymatically cleavable linkers) that have gained significant attention in ADC development due to their superior plasma stability and controled payload release mechanism.

Column Infos

Benzenes
Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.