Product Name:3-(chloromethyl)-3-methyloxetane

IUPAC Name:3-(chloromethyl)-3-methyloxetane

CAS:822-48-0
Molecular Formula:C5H9ClO
Purity:95%+
Catalog Number:CM104101
Molecular Weight:120.58

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CM104101-25g in stock ȷȦɐ
CM104101-100g in stock ȌȦDz

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Product Details

CAS NO:822-48-0
Molecular Formula:C5H9ClO
Melting Point:-
Smiles Code:CC1(CCl)COC1
Density:
Catalog Number:CM104101
Molecular Weight:120.58
Boiling Point:
MDL No:MFCD01709552
Storage:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

Column Infos

Alicyclic Heterocycles
When the ends of the chains are joined together into a ring, cyclic compounds result; such substances often are referred to as carbocyclic or alicyclic compounds. Substitution of one or more of the ring carbon atoms in the molecules of a carbocyclic compound with a heteroatom gives a heterocyclic compound.