Product Name:8-(Benzyloxy)-N-(4-((3-methyloxetan-3-yl)methoxy)-2-nitrophenyl)quinolin-2-amine

IUPAC Name:8-(benzyloxy)-N-{4-[(3-methyloxetan-3-yl)methoxy]-2-nitrophenyl}quinolin-2-amine

CAS:816463-37-3
Molecular Formula:C27H25N3O5
Purity:97%
Catalog Number:CM227306
Molecular Weight:471.51

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CM227306-1g in stock Əǎijǭ

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Product Details

CAS NO:816463-37-3
Molecular Formula:C27H25N3O5
Melting Point:-
Smiles Code:O=[N+](C1=CC(OCC2(C)COC2)=CC=C1NC3=NC4=C(OCC5=CC=CC=C5)C=CC=C4C=C3)[O-]
Density:
Catalog Number:CM227306
Molecular Weight:471.51
Boiling Point:
MDL No:MFCD12973805
Storage:

Category Infos

Quinolines
Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
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Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.