Product Name:(1R,2R,5S)-rel-3-(tert-Butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

IUPAC Name:(1R,2R,5S)-3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

CAS:72448-25-0
Molecular Formula:C11H17NO4
Purity:95%
Catalog Number:CM294701
Molecular Weight:227.26

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CM294701-1g 1-2 Weeks ȁȬNJ

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Product Details

CAS NO:72448-25-0
Molecular Formula:C11H17NO4
Melting Point:-
Smiles Code:O=C([C@H]1[C@]2([H])C[C@]2([H])CN1C(OC(C)(C)C)=O)O
Density:
Catalog Number:CM294701
Molecular Weight:227.26
Boiling Point:355.9°C at 760 mmHg
MDL No:MFCD22536388
Storage:Store at room temperature.

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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