Product Name:5-Maleimidovaleric acid

IUPAC Name:5-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid

CAS:57078-99-6
Molecular Formula:C9H11NO4
Purity:95%+
Catalog Number:CM129330
Molecular Weight:197.19

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Product Details

CAS NO:57078-99-6
Molecular Formula:C9H11NO4
Melting Point:-
Smiles Code:O=C(O)CCCCN1C(C=CC1=O)=O
Density:
Catalog Number:CM129330
Molecular Weight:197.19
Boiling Point:
MDL No:MFCD04115790
Storage:Store at room temperature.

Category Infos

Pyrrolines
Pyrrolines, also called dihydropyrroles, are obtained from aromatic pyrroles by hydrogenation. 1-pyrroline is a cyclic imine, while 2-pyrroline and 3-pyrroline are cyclic amines.
ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Maleimides
Thiol-maleimide is a bifunctional chemical compound that is commonly used in bioconjugation reactions to crosslink two molecules via the thiol (-SH) groups.
Non-cleavable linkers
Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.

Column Infos

Pyrroles
Pyrrole is a five membered heterocyclic compound with the molecular formula of C4H5N. Pyrrole has a ring composed of four carbon atoms and one nitrogen atom. Pyrrole is easy to polymerize in the air. Pyrrole is the parent compound of many important biological substances (such as bile pigment, porphyrin and chlorophyll). Pyrrole scaffolds are widely used in biological and pharmaceutical fields. Pyrrole is a special heterocyclic scaffold, which exists in many natural products, drug molecules and pesticides, and has shown its application in materials science.