cas 4933-14-6|| where to buy spiro[cyclohexane-1,3'-indolin]-2'-one

Product Name:spiro[cyclohexane-1,3'-indolin]-2'-one

IUPAC Name:1',2'-dihydrospiro[cyclohexane-1,3'-indol]-2'-one

: CAS：4933-14-6; Molecular Formula：C13H15NO; Purity：95%

: Catalog Number：CM139049; Molecular Weight：201.27

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CM139049-100mg	in stock	ŭǕ
CM139049-250mg	in stock	ȀȀƅ
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Product Details

: CAS NO:4933-14-6; Molecular Formula:C13H15NO; Melting Point:-; Smiles Code:O=C(C12CCCCC1)NC3=C2C=CC=C3; Density:

: Catalog Number:CM139049; Molecular Weight:201.27; Boiling Point:; MDL No:MFCD11935809; Storage:Store at 2-8°C.

Category Infos

: Cyclohexanes; Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.

: Indolinones; Indolinone derivatives have in common the presence of a hydrogen bond between the C-2 carbonyl and a hydrogen donor in a side chain, generally a pyrrole ring. Indolinone displays very promising antitumor properties by inhibiting various kinase families.

Column Infos

: Spiro Compounds; A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.

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