Product Name:5-Bromo-3-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)-1H-indole

IUPAC Name:5-bromo-3-{1,4-dioxaspiro[4.5]dec-7-en-8-yl}-1H-indole

CAS:282546-99-0
Molecular Formula:C16H16BrNO2
Purity:95%
Catalog Number:CM213580
Molecular Weight:334.21

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Product Details

CAS NO:282546-99-0
Molecular Formula:C16H16BrNO2
Melting Point:-
Smiles Code:BrC1=CC2=C(NC=C2C(CC3)=CCC43OCCO4)C=C1
Density:
Catalog Number:CM213580
Molecular Weight:334.21
Boiling Point:
MDL No:
Storage:Store at 2-8°C.

Category Infos

Indoles
Indole is a compound of pyrrole and benzene in parallel, also known as benzopyrrole. There are two combinations of pyrrole and benzene, called indole and isoindole, respectively. Many derivatives of indole have physiological and pharmacological activities, and can synthesize vasodilators, antihistamines, antipyretic analgesics, etc. in medicine, so indole is also a very important heterocyclic compound.
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Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
Spiro And Bicyclic Compound
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Dioxolanes
Dioxolane is a heterocyclic acetal with the formula (CH2)2O2CH2. It is related to tetrahydrofuran by exchanging an oxygen for the CH2 group. The isomer 1,2-dioxolane (in which the two oxygen centers are adjacent) is a peroxide. 1,3-Dioxolane is used as solvent and comonomer in polyacetal. The dioxolane-type and their hydrogenolysis can provide very valuable partially protected building blocks either for oligosaccharide syntheses or sugar transformations.

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