Product Name:1-(3-ethynylphenyl)hexahydropyrimidine-2,4-dione

IUPAC Name:1-(3-ethynylphenyl)-1,3-diazinane-2,4-dione

CAS:2633725-36-5
Molecular Formula:C12H10N2O2
Purity:95%
Catalog Number:CM1077306
Molecular Weight:214.22

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Product Details

CAS NO:2633725-36-5
Molecular Formula:C12H10N2O2
Melting Point:-
Smiles Code:O=C1CCN(C(=O)N1)C1=CC(=CC=C1)C#C
Density:
Catalog Number:CM1077306
Molecular Weight:214.22
Boiling Point:
MDL No:
Storage:

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PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.