Product Name:4-((1H-Indazol-6-yl)amino)-6-methoxy-7-(3-morpholino-propoxy)quinoline-3-carbonitrile

IUPAC Name:4-[(1H-indazol-6-yl)amino]-6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinoline-3-carbonitrile

CAS:263170-58-7
Molecular Formula:C25H26N6O3
Purity:95%
Catalog Number:CM143627
Molecular Weight:458.52

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CM143627-250mg in stock ƚƴƴ

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Product Details

CAS NO:263170-58-7
Molecular Formula:C25H26N6O3
Melting Point:-
Smiles Code:COC1=CC2=C(C=C1OCCCN1CCOCC1)N=CC(C#N)=C2NC1=CC=C2C=NNC2=C1
Density:
Catalog Number:CM143627
Molecular Weight:458.52
Boiling Point:
MDL No:
Storage:Store at 2-8°C.

Category Infos

Morpholines
Morpholine contains secondary amine groups and has all the typical reactive characteristics of secondary amine groups. It can react with inorganic acids to form salts, and react with organic acids to form salts or amides, which can be subjected to alkylation reaction, and can also be reacted with ethylene oxide, ketone or Willgerodt reaction. Morpholine is a six-membered ring containing oxygen and nitrogen, and its alkalinity is much lower than that of its parent piperidine. The marketed morpholine drugs are mainly distributed in the fields of tumors, cardiovascular and cerebrovascular diseases, respiratory system diseases, digestive system diseases, infectious diseases and mental disorders.
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Quinolines
Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
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Indazoles
Indazoles are a class of organic heterocyclic compounds, also known as 1,2-diazaindene and benzopyrazole. Indazole is a good bioisomer of phenol, which is more lipophilic than phenol and less prone to phase I and II metabolism. Indazole derivatives have a wide range of biological activities, and it has been confirmed that indazole compounds have anti-tumor, analgesic, anti-inflammatory and other drug activities. Anticancer is the most important application field of indazole drugs. Renal cell carcinoma, solid tumor, nausea and vomiting caused by chemotherapy and leukemia are the main indications of this structural backbone drug.