Product Name:3-(1-oxo-4-prop-2-ynoxy-isoindolin-2-yl)piperidine-2,6-dione

IUPAC Name:3-[1-oxo-4-(prop-2-yn-1-yloxy)-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione

CAS:2434750-54-4
Molecular Formula:C16H14N2O4
Purity:95%
Catalog Number:CM1077325
Molecular Weight:298.3

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Product Details

CAS NO:2434750-54-4
Molecular Formula:C16H14N2O4
Melting Point:-
Smiles Code:O=C1N(CC2=C(OCC#C)C=CC=C12)C1CCC(=O)NC1=O
Density:
Catalog Number:CM1077325
Molecular Weight:298.3
Boiling Point:
MDL No:
Storage:

Category Infos

PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.

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