Product Name:Ethyl 2,2-difluorobutanoate

IUPAC Name:ethyl 2,2-difluorobutanoate

CAS:2368-92-5
Molecular Formula:C6H10F2O2
Purity:95%+
Catalog Number:CM418339
Molecular Weight:152.14

Packing Unit Available Stock Price($) Quantity
CM418339-1g 3-4 Weeks Ⱥǜư

For R&D use only.

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Product Details

CAS NO:2368-92-5
Molecular Formula:C6H10F2O2
Melting Point:-
Smiles Code:CCOC(=O)C(F)(F)CC
Density:
Catalog Number:CM418339
Molecular Weight:152.14
Boiling Point:
MDL No:
Storage:

Column Infos

LEI-515
The recent publication titles “Structure–Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors”. Monoacylglycerol lipase (MAGL) is the critical enzyme responsible for the hydrolysis of endocannabinoid 2-arachidonoylglycerol (2-AG) to arachidonate and glycerol, contributing to the inflammatory cascade in the CNS. MAGL inhibition provides various potential therapeutic opportunities, including inflammation-induced tissue injury, pain, multiple sclerosis, and cancer.
LEI-515 is an aryl sulfoxide, and a peripherally restricted, covalent reversible MAGL inhibitor. LEI-515 increases 2-AG levels in the periphery and reduces neuropathic pain and inflammation, without inducing CNS adverse effects or physical dependence.