Product Name:(3-Cyano-4-(oxetan-3-yl)phenyl)boronic acid

IUPAC Name:[3-cyano-4-(oxetan-3-yl)phenyl]boronic acid

CAS:2256708-83-3
Molecular Formula:C10H10BNO3
Purity:95%+
Catalog Number:CM1048878
Molecular Weight:203

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CM1048878-25mg in stock ǙǪƈ
CM1048878-100mg in stock ǸŤǪƴ

For R&D use only.

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Product Details

CAS NO:2256708-83-3
Molecular Formula:C10H10BNO3
Melting Point:-
Smiles Code:N#CC1=CC(B(O)O)=CC=C1C2COC2
Density:
Catalog Number:CM1048878
Molecular Weight:203
Boiling Point:
MDL No:
Storage:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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