Product Name:N-[2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindolin-4-yl]-8-(hydroxyamino)-8-oxo-octanamide

IUPAC Name:N'-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]-N-hydroxyoctanediamide

CAS:2233579-08-1
Molecular Formula:C21H26N4O6
Purity:95%
Catalog Number:CM1077512
Molecular Weight:430.46

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Product Details

CAS NO:2233579-08-1
Molecular Formula:C21H26N4O6
Melting Point:-
Smiles Code:ONC(=O)CCCCCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1
Density:
Catalog Number:CM1077512
Molecular Weight:430.46
Boiling Point:
MDL No:
Storage:

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PROTAC-E3 Ligase Ligands
Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.