Product Name:6-Fluoro-2-azaspiro[3.3]heptane; trifluoroacetic acid

IUPAC Name:6-fluoro-2-azaspiro[3.3]heptane; trifluoroacetic acid

CAS:2227205-88-9
Molecular Formula:C8H11F4NO2
Purity:95%+
Catalog Number:CM471308
Molecular Weight:229.18

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Product Details

CAS NO:2227205-88-9
Molecular Formula:C8H11F4NO2
Melting Point:-
Smiles Code:OC(=O)C(F)(F)F.FC1CC2(CNC2)C1
Density:
Catalog Number:CM471308
Molecular Weight:229.18
Boiling Point:
MDL No:MFCD31695984
Storage:

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Cyclobutanes
The molecular structure of cyclobutane has four carbon atoms, and its four carbon atoms are not in the same plane, which is the folded conformation of cyclobutane. Cyclobutane itself is not of commercial or biological interest, but more complex derivatives are important in biology and biotechnology. Currently, nine FDA-approved drugs contain the cyclobutane structure. From the perspective of therapeutic areas, cyclobutyl drugs are mainly distributed in popular areas such as tumors, neurological diseases, infectious diseases, endocrine and metabolic diseases.

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