cas 1932477-04-7|| where to buy ethyl(1R,4S,5S,6S)-4-hydroxy-2-thiabicyclo[3.1.0]hexane-6-carboxylate

Product Name:ethyl(1R,4S,5S,6S)-4-hydroxy-2-thiabicyclo[3.1.0]hexane-6-carboxylate

IUPAC Name:ethyl (1R,4S,5S,6S)-4-hydroxy-2-thiabicyclo[3.1.0]hexane-6-carboxylate

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: CAS NO:1932477-04-7; Molecular Formula:C8H12O3S; Melting Point:-; Smiles Code:CCOC(=O)[C@H]1[C@@H]2SC[C@@H](O)[C@H]12; Density:

: Catalog Number:CM405027; Molecular Weight:188.24; Boiling Point:; MDL No:; Storage:

: Cyclopropanes; Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

: Tetrahydrothiophenes; Tetrahydrothiophene is a sulfur-containing saturated heterocyclic compound obtained by catalytic hydrogenation of thiophene. After thiophene is reduced to tetrahydrothiophene, it no longer has a conjugated system and aromaticity. Therefore, tetrahydrothiophene shows the properties of general thioethers. Easily oxidized to sulfoxides and sulfones. Tetrahydrothiophene can be used as a raw material for the production of pharmaceuticals, pesticides and photochemicals.