Product Name:6-(Chloromethyl)uracil
IUPAC Name:6-(chloromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
Product Overview |
6-(Chloromethyl)uracil, also known as 6-CMU, is a chlorinated derivative of uracil, a pyrimidine base that is present in RNA. 6-CMU has been studied for its potential applications in medicine, biochemistry, and other scientific research fields. It has been used to study the effects of mutagenesis, to synthesize nucleic acid analogues, and to investigate the mechanism of action of certain enzymes. |
Synthesis and Application |
6-(Chloromethyl)uracil can be synthesized in a two-step process. The first step involves the reaction of uracil with thionyl chloride to produce 5-chlorouracil. In the second step, 5-chlorouracil is reacted with sodium ethoxide to yield 6-(Chloromethyl)uracil. This reaction is highly efficient, with yields of up to 95%. 6-(Chloromethyl)uracil has been used in many scientific research applications, including its use as a mutagenic agent for studying the effects of genetic mutations. It has also been used to synthesize nucleic acid analogues, which can be used to study the structure and function of DNA and RNA. Additionally, 6-(Chloromethyl)uracil has been used to investigate the mechanism of action of certain enzymes, such as DNA polymerase. |
Future Directions |
There are many potential future directions for the use of 6-(Chloromethyl)uracil in scientific research. One potential direction is to use 6-(Chloromethyl)uracil to study the effects of gene expression on cancer cells. Additionally, 6-(Chloromethyl)uracil could be used to study the effects of epigenetic modifications on gene expression. Finally, 6-(Chloromethyl)uracil could be used to study the effects of gene therapy on various diseases. |