Product Name:2-((2-Aminopyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)quinoline-5-carboxamide

IUPAC Name:2-[(2-aminopyrimidin-4-yl)oxy]-N-[3-(trifluoromethyl)phenyl]quinoline-5-carboxamide

CAS:1631035-78-3
Molecular Formula:C21H14F3N5O2
Purity:95%
Catalog Number:CM222988
Molecular Weight:425.37

Packing Unit Available Stock Price($) Quantity
CM222988-1g in stock ƀȁƎ

For R&D use only.

Inquiry Form

   refresh    

Product Details

CAS NO:1631035-78-3
Molecular Formula:C21H14F3N5O2
Melting Point:-
Smiles Code:O=C(C1=C2C=CC(OC3=NC(N)=NC=C3)=NC2=CC=C1)NC4=CC=CC(C(F)(F)F)=C4
Density:
Catalog Number:CM222988
Molecular Weight:425.37
Boiling Point:
MDL No:MFCD26403996
Storage:

Category Infos

Quinolines
Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
Quinoline Price
if you have any question on quinoline price, we will give the professional answers to your short questions.
Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.