Product Name:Tert-Butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamate
IUPAC Name:tert-butyl N-{4-aminobicyclo[2.2.2]octan-1-yl}carbamate
Product Overview |
Tert-Butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamate, also known as t-Boc-Aminocyclopentane, is a versatile and widely used carbamate in various fields of science. It is a commonly used reagent in organic synthesis and has many applications in the fields of biochemistry, pharmaceuticals, and materials science. |
Physical Properties |
It is a white crystalline solid that is soluble in common organic solvents such as methanol, ethanol, and acetone. |
Synthesis and Application |
Tert-butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamate can be synthesized by reacting tert-butyl isocyanate with 4-aminocyclopentane in the presence of a base. The reaction is typically carried out in an organic solvent such as dichloromethane or toluene at temperatures ranging from 0 to 50°C. The reaction is complete when the reaction mixture is neutralized with an acid such as hydrochloric acid. Tert-butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamate has a variety of scientific research applications. It is commonly used as a protecting group for amines in peptide synthesis, as a reagent in the synthesis of peptides, as a catalyst for the preparation of cyclic carbonates, and as a reagent in the synthesis of heterocyclic compounds. Additionally, it has been used in the development of peptide-based drugs, the synthesis of peptide-based vaccines, and the synthesis of peptide-based contrast agents for magnetic resonance imaging (MRI). |
Future Directions |
The future of tert-butyl (4-aminobicyclo[2.2.2]octan-1-yl)carbamate is promising. It is a versatile reagent with a variety of applications in organic synthesis. It can be used to synthesize peptides, cyclic carbonates, and heterocyclic compounds. Additionally, it can be used in the development of peptide-based drugs, peptide-based vaccines, and peptide-based contrast agents for MRI. Furthermore, research is ongoing to develop new methods for the synthesis of peptides using tert-butyl carbamate. Finally, new derivatives of tert-butyl carbamate are being developed for use as protecting groups in peptide synthesis. |