Product Name:sodium 1,1'-((3,3'-disulfanediylbis(propanoyl))bis(oxy))bis(2,5-dioxopyrrolidine-3-sulfonate)

IUPAC Name:2,5-dioxo-3-[(sodiooxy)sulfonyl]pyrrolidin-1-yl 3-{[3-({2,5-dioxo-3-[(sodiooxy)sulfonyl]pyrrolidin-1-yl}oxy)-3-oxopropyl]disulfanyl}propanoate

CAS:142702-31-6
Molecular Formula:C14H14N2Na2O14S4
Purity:95%+
Catalog Number:CM534370
Molecular Weight:608.49

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CM534370-1g 1-2 Weeks ŮǙǪƿ

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Product Details

CAS NO:142702-31-6
Molecular Formula:C14H14N2Na2O14S4
Melting Point:-
Smiles Code:O=C(CCSSCCC(ON1C(CC(S(=O)(O[Na])=O)C1=O)=O)=O)ON2C(CC(S(=O)(O[Na])=O)C2=O)=O
Density:
Catalog Number:CM534370
Molecular Weight:608.49
Boiling Point:
MDL No:
Storage:

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Cleavable linkers
Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.
N-Hydroxysuccinimide (NHS)
N-Hydroxysuccinimide
Disulfides/Thiols
In chemistry, a disulfide is a compound containing a R−S−S−R′ functional group or the S 2− anion. Thiols are the sulfur analogue of alcohols.