Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.
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Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.
Triazole refers to a heterocyclic compound with the molecular formula C2H3N3, which has a five-membered ring consisting of two carbon atoms and three nitrogen atoms. Neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease already affect many people around the world, and these numbers are increasing rapidly. Treatment for these disorders is often aimed at relieving symptoms and has no cure. Research on new molecules is underway, and heterocyclic compounds have important pharmacological implications. Triazoles and tetrazoles are emerging as new molecules in this field.
Carbazoles are an important class of nitrogen-containing heterocycles with a planar tricyclic skeleton consisting of two benzene rings fused on both sides of the central pyrrole ring, with a large aromatic system and a central nitrogen atom, showing broad of electron delocalization. The structure of this compound is based on the indole structure, but in which a second benzene ring is fused to a five-membered ring at positions 2-3 of the indole. Carbazole structural motifs are widely found in, but not limited to, a large number of natural alkaloids of plant or bacterial origin. Since many of these alkaloids are medically useful, exhibit a fairly wide range of biological activities (anticancer, anti-HIV, antibacterial, anti-Alzheimer's disease, anticoagulant, analgesic, antiepileptic, antidiabetic, antioxidant, etc.). Medicinal chemistry also uses carbazole motifs in synthetic drugs to combat hypertension, heart disease, and hepatitis C virus replication.
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Organic light emitting diodes (devices) or OLEDs are monolithic solid-state devices that typically consist of a series of organic thin films sandwiched between two thin film conductive electrodes. It is a display technology used in many electronic devices, such as smartphones, televisions, and wearables. In an OLED display, each pixel is made up of organic compounds that emit light when an electric current passes through them. Unlike traditional LCD displays, this eliminates the need for a backlight. As a result, OLED displays can achieve deeper blacks and higher contrast ratios, leading to vibrant and more realistic images.
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