Product Name:tert-butyl 3-(1-aminocyclopropyl)azetidine-1-carboxylate

IUPAC Name:tert-butyl 3-(1-aminocyclopropyl)azetidine-1-carboxylate

CAS:1352012-69-1
Molecular Formula:C11H20N2O2
Purity:95%+
Catalog Number:CM106565
Molecular Weight:212.29

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CM106565-250mg in stock ȡƎŵ
CM106565-1g 3-4 Weeks ƿƿǜƿ

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Product Details

CAS NO:1352012-69-1
Molecular Formula:C11H20N2O2
Melting Point:-
Smiles Code:O=C(N1CC(C2(N)CC2)C1)OC(C)(C)C
Density:
Catalog Number:CM106565
Molecular Weight:212.29
Boiling Point:
MDL No:
Storage:

Category Infos

Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos

Alicyclic Heterocycles
When the ends of the chains are joined together into a ring, cyclic compounds result; such substances often are referred to as carbocyclic or alicyclic compounds. Substitution of one or more of the ring carbon atoms in the molecules of a carbocyclic compound with a heteroatom gives a heterocyclic compound.

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