Product Name:tert-Butyl 4-(oxetan-3-yl)piperazine-1-carboxylate

IUPAC Name:tert-butyl 4-(oxetan-3-yl)piperazine-1-carboxylate

CAS:1257293-88-1
Molecular Formula:C12H22N2O3
Purity:95%
Catalog Number:CM169392
Molecular Weight:242.32

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CM169392-250mg in stock ȦɅ
CM169392-1g in stock ǧƱǧ

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Product Details

CAS NO:1257293-88-1
Molecular Formula:C12H22N2O3
Melting Point:-
Smiles Code:O=C(N1CCN(C2COC2)CC1)OC(C)(C)C
Density:
Catalog Number:CM169392
Molecular Weight:242.32
Boiling Point:
MDL No:MFCD22123277
Storage:

Category Infos

Piperazines
Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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