Product Name:2,4-Dichloropyrimidine-5-carboxamide

IUPAC Name:2,4-dichloropyrimidine-5-carboxamide

CAS:1240390-28-6
Molecular Formula:C5H3Cl2N3O
Purity:97%
Catalog Number:CM167387
Molecular Weight:192

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Product Details

CAS NO:1240390-28-6
Molecular Formula:C5H3Cl2N3O
Melting Point:-
Smiles Code:O=C(C1=CN=C(Cl)N=C1Cl)N
Density:
Catalog Number:CM167387
Molecular Weight:192
Boiling Point:
MDL No:MFCD16658133
Storage:Keep in dark place, inert atmosphere, store at 2-8°C.

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

Column Infos

Cerdulatinib
Cerdulatinib is a small molecule SYK/JAK kinase inhibitor in development for treatment of hematological malignancies. It has lowest nM IC50 values against TYK2, JAK1, JAK2, JAK3, FMS, and SYK. Cerdulatinib is a reversible ATP-competitive dual JAK and Syk inhibitor. The FDA granted orphan drug status to cerdulatinib for the treatment of peripheral T-cell lymphoma (PTCL).