Product Name:2-Chloro-5-(difluoromethoxy)pyrimidine

IUPAC Name:2-chloro-5-(difluoromethoxy)pyrimidine

CAS:1192813-64-1
Molecular Formula:C5H3ClF2N2O
Purity:95%+
Catalog Number:CM325391
Molecular Weight:180.54

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Product Details

CAS NO:1192813-64-1
Molecular Formula:C5H3ClF2N2O
Melting Point:-
Smiles Code:FC(F)OC1=CN=C(Cl)N=C1
Density:
Catalog Number:CM325391
Molecular Weight:180.54
Boiling Point:260.1±30.0°C at 760 mmHg
MDL No:MFCD18415615
Storage:

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

Column Infos

AZD0780
AstraZeneca announced Phase I trial data for its PCSK9 inhibitor, AZD0780. AZD0780 is an oral small molecule PCSK9 inhibitor as a first-in-class therapy for patients with dyslipidemia that cannot be controlled by statins alone. PSCK9 is a well-known and validated target in lipid metabolism and inhibiting PSCK9 signalling has shown to be effective in reducing LDL cholesterol levels in plasma. Lower LDL-C levels are associated with a reduction in the risk of long-term cardiovascular disease and major cardiovascular events.
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