Product Name:2-fluoro-6-(2H-1,2,3-triazol-2-yl)benzoic acid

IUPAC Name:2-fluoro-6-(2H-1,2,3-triazol-2-yl)benzoic acid

CAS:1186050-58-7
Molecular Formula:C9H6FN3O2
Purity:95%+
Catalog Number:CM130835
Molecular Weight:207.16

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Product Details

CAS NO:1186050-58-7
Molecular Formula:C9H6FN3O2
Melting Point:-
Smiles Code:O=C(O)C1=C(N2N=CC=N2)C=CC=C1F
Density:
Catalog Number:CM130835
Molecular Weight:207.16
Boiling Point:410.5±55.0°C at 760 mmHg
MDL No:MFCD23135320
Storage:Keep in a tight container,store at ambient temperature for short term and store at 2°C~8°C for lont term

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Triazoles
Triazole refers to a heterocyclic compound with the molecular formula C2H3N3, which has a five-membered ring consisting of two carbon atoms and three nitrogen atoms. Neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease already affect many people around the world, and these numbers are increasing rapidly. Treatment for these disorders is often aimed at relieving symptoms and has no cure. Research on new molecules is underway, and heterocyclic compounds have important pharmacological implications. Triazoles and tetrazoles are emerging as new molecules in this field.

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Benzenes
Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.
Seltorexant
Johnson & Johnson pivotal study of Seltorexant shows statistically significant and clinically meaningful improvement in depressive symptoms and sleep disturbance outcomes. Seltorexant meets all primary and secondary endpoints in the pivotal Phase 3 MDD3001 clinical trial of adult and elderly patients with major depressive disorder (MDD) with insomnia symptoms.
Orexin signaling pathways are found to be associated with depression and anxiety. Orexin neurons receive and transmit signals throughout the central nervous system (CNS) that are modulated by their specific receptors (OX1R, OX2R). Seltorexant is an investigational first-in-class selective antagonist of ORX2 receptor. It is developed as an adjunctive therapy for MDD and for the treatment of insomnia disorder.

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