Product Name:6-(Cyclopropylamino)pyridazine-3-carboxylic Acid

IUPAC Name:6-(cyclopropylamino)pyridazine-3-carboxylic acid

CAS:1178768-37-0
Molecular Formula:C8H9N3O2
Purity:95%
Catalog Number:CM324433
Molecular Weight:179.18

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CM324433-1g 1-2 Weeks ǺǠǺ

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Product Details

CAS NO:1178768-37-0
Molecular Formula:C8H9N3O2
Melting Point:-
Smiles Code:O=C(C1=NN=C(NC2CC2)C=C1)O
Density:
Catalog Number:CM324433
Molecular Weight:179.18
Boiling Point:
MDL No:MFCD12152627
Storage:

Category Infos

Pyridazines
Pyridazine, also known as o-diazobenzene, is a six-membered heterocyclic compound containing two nitrogen heteroatoms in the 1 and 2 positions with a special structure and a wide biological activity. Pyridazine is more and more popular in drug development, and a variety of pyridazine drugs have been developed and marketed. From the perspective of the therapeutic field, pyridazine drug molecules are mainly used for tumor treatment, but also involve in many therapeutic fields such as inflammation, hypertension and cardiovascular disease. With the increase and in-depth of research, pyridazine drugs will play more roles in the treatment of diseases.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Product Other Information

Product Overview 6-(Cyclopropylamino)pyridazine-3-carboxylic Acid (1178768-37-0) is a novel pyridazine derivative that has attracted significant attention due to its potential as a therapeutic agent. 6-(Cyclopropylamino)pyridazine-3-carboxylic Acid has been shown to exhibit potent inhibitory activity against a range of enzymes, including kinases and phosphodiesterases, making it a promising candidate for the treatment of various diseases.
Chemical Properties 6-(Cyclopropylamino)pyridazine-3-carboxylic Acid is a reactive compound, often utilized as a starting material or intermediate in various chemical reactions and synthesis processes.
Synthesis and Application 6-(Cyclopropylamino)pyridazine-3-carboxylic Acid has been extensively studied for its potential as a therapeutic agent. It has been shown to exhibit potent inhibitory activity against a range of enzymes, including cGMP-specific phosphodiesterase type 5 (PDE5), which is a key target for the treatment of erectile dysfunction. 6-(Cyclopropylamino)pyridazine-3-carboxylic Acid has also been shown to inhibit various kinases, including mitogen-activated protein kinase (MAPK) and cyclin-dependent kinase (CDK), which are involved in the regulation of cell growth and division.