Product Name:2'-Hydroxygenistein
IUPAC Name:3-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
Product Overview |
2'-Hydroxygenistein (2-HG) is a naturally occurring polyphenol compound found in various plants, including soybean, tea, and coffee. It is an important metabolite in the human body and is thought to be involved in many physiological processes. 2-HG has been studied for its potential therapeutic properties, including anti-cancer, anti-inflammatory, and antioxidant activities, as well as its ability to modulate gene expression. |
Synthesis and Application |
2'-Hydroxygenistein can be synthesized from the oxidation of 2-hydroxybenzaldehyde, which is typically obtained from the hydrolysis of plant-derived polyphenols such as catechins. The oxidation is typically carried out in the presence of a metal catalyst, such as copper or iron, and in an acidic medium. The reaction is usually performed at room temperature and is usually complete within a few hours. 2'-Hydroxygenistein has been studied for its potential therapeutic properties, including anti-cancer, anti-inflammatory, and antioxidant activities, as well as its ability to modulate gene expression. It has been shown to inhibit the growth of various cancer cell lines, including breast, prostate, and colorectal cancer. It has also been shown to reduce inflammation in animal models and has been shown to have antioxidant and anti-aging effects in vitro. In addition, 2'-Hydroxygenistein has been shown to modulate gene expression, which may be useful in the treatment of various diseases. |
Future Directions |
There are several potential future directions for research into 2'-Hydroxygenistein. One potential direction is to further investigate its mechanism of action and its effects on gene expression. Another potential direction is to further investigate its potential therapeutic properties, such as its anti-cancer, anti-inflammatory, and antioxidant activities. In addition, further research could be conducted into its potential applications in the pharmaceutical and food industries. Finally, further research could be conducted into its potential as a biomarker for various diseases. |