Product Name:5-(3-Chloro-4-fluorophenyl)-3-methyl-3-(pyrimidin-5-ylmethyl)indolin-2-one

IUPAC Name:5-(3-chloro-4-fluorophenyl)-3-methyl-3-[(pyrimidin-5-yl)methyl]-2,3-dihydro-1H-indol-2-one

CAS:1141080-83-2
Molecular Formula:C20H15ClFN3O
Purity:95%
Catalog Number:CM148355
Molecular Weight:367.81

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Product Details

CAS NO:1141080-83-2
Molecular Formula:C20H15ClFN3O
Melting Point:-
Smiles Code:O=C1NC2=C(C=C(C3=CC=C(F)C(Cl)=C3)C=C2)C1(C)CC4=CN=CN=C4
Density:
Catalog Number:CM148355
Molecular Weight:367.81
Boiling Point:
MDL No:MFCD22572947
Storage:Store at 2-8°C.

Category Infos

Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Indolinones
Indolinone derivatives have in common the presence of a hydrogen bond between the C-2 carbonyl and a hydrogen donor in a side chain, generally a pyrrole ring. Indolinone displays very promising antitumor properties by inhibiting various kinase families.