Product Name:5-Amino-3-(trifluoromethyl)isoxazol

IUPAC Name:3-(trifluoromethyl)-1,2-oxazol-5-amine

CAS:108655-63-6
Molecular Formula:C4H3F3N2O
Purity:95%+
Catalog Number:CM119107
Molecular Weight:152.08

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CM119107-250mg in stock ůŗ
CM119107-1g in stock ȃůƓ
CM119107-5g in stock ŹůIJ

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Product Details

CAS NO:108655-63-6
Molecular Formula:C4H3F3N2O
Melting Point:-
Smiles Code:FC(C1=NOC(N)=C1)(F)F
Density:
Catalog Number:CM119107
Molecular Weight:152.08
Boiling Point:
MDL No:MFCD04972407
Storage:Keep in dark place, store at 2-8°C.

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Isoxazoles
Isoxazole is a liquid heterocyclic compound C3H3NO isomeric with oxazole and having a penetrating odor like that of pyridine. Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, nitrogen and oxygen, in a 1,2-relationship and three regular sp2 carbon atoms. These molecules are found to be key components in various synthetic products in daily use and also present as a pharmacophore essential for biological activity in many drugs and bioactive natural products. In addition, isoxazoles have demonstrated their ability to exhibit hydrogen bond donor/acceptor interactions with a variety of enzymes and receptors.

Column Infos

Oxazoles
Oxazoles are heterocyclic aromatic compounds containing one oxygen atom and one nitrogen atom, separated by a carbon atom. The presence of two heteroatoms (oxygen and nitrogen) provides possible interactions (hydrogen, hydrophobic, van der Waals or dipole bonds) with a wide range of receptors and enzymes. Oxazole rings are valuable heterocyclic scaffolds for the design of novel therapeutics with anticancer, antiviral, antibacterial, anti-inflammatory, neuroprotective, antidiabetic, and antidepressant properties due to their wide range of targets and biological activities.