Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Azaindole can be regarded as the biological isostere of indole, and the molecular unit of indole plays a huge role in the life process. Many drug molecules contain indole units. Azaindole is an important heterocyclic intermediate with good biological and medicinal value, and is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, kinase inhibitors, thrombin inhibitors, etc. Therefore, it has a wide range of application value in medical research. Azaindole can be regarded as the biological isostere of indole, and the molecular unit of indole plays a huge role in the life process. Many drug molecules contain indole units. Azaindole is an important heterocyclic intermediate with good biological and medicinal value, and is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, kinase inhibitors, thrombin inhibitors, etc. Therefore, it has a wide range of application value in medical research.Azaindole
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