Product Name:3-(iodomethyl)oxetane

IUPAC Name:3-(iodomethyl)oxetane

CAS:1003013-77-1
Molecular Formula:C4H7IO
Purity:95%+
Catalog Number:CM105456
Molecular Weight:198

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Product Details

CAS NO:1003013-77-1
Molecular Formula:C4H7IO
Melting Point:-
Smiles Code:ICC1COC1
Density:
Catalog Number:CM105456
Molecular Weight:198
Boiling Point:
MDL No:MFCD18909284
Storage:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

Column Infos

Alicyclic Heterocycles
When the ends of the chains are joined together into a ring, cyclic compounds result; such substances often are referred to as carbocyclic or alicyclic compounds. Substitution of one or more of the ring carbon atoms in the molecules of a carbocyclic compound with a heteroatom gives a heterocyclic compound.